Frank D. Mann, Ph.D.

I am a Senior Research Scientist at Stony Brook University in the Department of  Medicine and a statistical reviewer for JAMA Network Open. My work investigates how psychosocial and environmental stressors accumulate and change across the life span to influence mental and physical health. By developing multidimensional models, I quantify the stress exposome—weighting diverse domains such as discrimination, interpersonal strain, and financial hardship—and track these trajectories over decades. My work links acute and chronic stressors to PTSD, multimorbidity, mild cognitive impairment, and dementia, while integrating genetic liability and immune-inflammatory pathways to illuminate underlying etiology. I approach these and related topics using theories and methods from differential and clinical psychology, life course epidemiology, biostatistics, and quantitative genetics. Some of my recent work has been published in Nature Mental Health, American Psychologist, American Journal of Industrial Medicine, and World Psychiatry. In 2021, I received the Early Career Award from the International Society for the Study of Individual Differences. Previously, I completed a postdoctoral appointment at the University of Minnesota, worked as a statistical consultant for the Center for Practice Transformation, and taught longitudinal data analysis, research methods, and statistics.